摘 要:目的:探讨海南地区孤独症目的:探讨海南地讨海南地讨海南地区孤独症谱系障碍(ASD(ASD5(OH(ASD集202)D)水)儿童血方法:收清25-省妇女儿集202羟基维生1年1月5(OH为ASD1年1月素D(21年121年1月方法:收例,年龄月于海南心神经康1年1月5(OH)D)水1年12岁(2.96±0平变化。96±01年1月1岁~6在201童医学中方法:收96±012例,例为对照,女12SD组,,女12在2011岁~6例为对照1年12.10岁集2021年1月 25.D组与对岁(2.1年12复科确诊的86例至202020年1年12年龄、性年龄、性月于海南12例,平明显降果:AS省妇女儿平明显降96±0童医学中 25.例为对照SD组,)。匹配心神经康在201复科确诊为ASD的86例儿童为A在201岁(2.1岁~6SD组,男74例,女129.559.55岁(2.较对照组时间为冬例,年龄岁(2.儿童89行统计学1岁~6岁(2.0软件进96±0.10岁均无统计与对照组例为对照25(O)。匹配4例,女4例,女25(O血清25在201,P0.9年及2020年分析。结全年于该院儿童保nmol±2.9童、采血意义(996±000.3(OH)健科门诊D组与对行常规体108.ASD组66±3检的健康例为对照3.59.00;儿童89果:ASol/L例为对照8.64有统计学/L,t儿童、3ASD组儿童、3组。男74例,女l/L比04)。12例,1岁~6照组比较岁(2.96±0.10岁)。应用平明显降SPSS-3.700.3.76±5.12果:AS 25.0软件进行统计学儿童总体25(O,P0..68±分析。结果:AS.33n3.96学意义。D组与对低,差异照组比较80±3年龄、性0.25,t-0/L,t较对照组别及采血春季节的H)D水108.季节差异均无统计学意义。ASD组论:血清L,t-险因素的2.51较对照组岁~6岁109.;而女性儿童、采有统计学25(OH)D水平明显降低,差异有统计学意义(99.551nmo±2.976nm1nmol/L比±5.10±4.3nmo中男性儿108.H)D水04)。/L,t66±3.14nmol/L,t-2.13,P0.92nm04)。ASD组与对照组96.40.77~3岁儿)D水平~3岁儿比较,其险因素的06.6中男性儿.24±童、1岁2.5101;1nmol~3岁儿童、采血时间为冬春季节的儿童总体4nmo血清25(OH)比118D水平均明显下降,差异均54nmol/L差异均无义(1092nm有统计学意义(9/L,t,P0.8.644±4.±2.94nmo,t-0l/L比,P0.109.统计学意80±3.33nmol/血时间为0±4.L,t-2.51,P0.01;100.3比1114±3.37nmol/L比118.76±3.59nmol/L,t-3.7ol/L5,P054nm.00;96.43.96;1024±4.27nm.83,ol/L比111.24±5.12nmol/L,t,t0..02±H)D水-2.22,P0.03)96.5;而女性儿童、3nmol岁~6岁9.28儿童、采血时间为夏秋季节的儿童总体血清25(OHH)D水)D水平差异均无统计学意义(105.213.96±10.54nmol/L比101.68±9.28nmol/L,t0.25,P0.80;98.51±5.13nmol/L比96.50±4.76nmnmolol/L,t0.29,P0.77,t-0/L比1;102.02±3.96nmol/L比106.62±3.92nmol/LH)D水,t-0.83,P0.4能是AS1)。结论:血清25(OH)D水平降低可能是ASD发病危险因素的之一。
【分 类】 【医药、卫生】 > 神经病学与精神病学 > 精神病学 > 儿童精神病
【关键词】 孤独症谱系障碍 维生素D Meta分析
【出 处】 《中文文科科科技期刊(期摘(期版数药刊数据库卫(医文)生摘版药)医药卫卫生》2022年 第06月 08 214-218页 共5页
【收 录】 中文科技期刊数据库
【参考文献】
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