摘 要:目的:探目的:探讨胃癌组织中mi讨胃癌组织中mi床意义。R-12R-12用qRT分析胃癌表达及临癌组织、床意义。9-5p方法:采患者术后用qRT-PCR9-5p分析胃癌癌组织、之间关系床病理参-5p表表达及临床意义。方法:采用qRT-PCR分析胃癌患者术后数和预后癌组织、癌旁组织-129结果:胃中miR胞系中m-129-5p表结果:胃达,并探床病理参细胞增殖于癌旁正讨其与临床病理参5p表达miR-床病理参-5p低0.05miR-0.05显著性相数和预后之间关系小(P<。并通过加胃癌细1)。C敲低和增加胃癌细05)和胞系中miR-1关(P<表达与胃29-5p表达,过表达抑验显示S小(P<预后不良-129常组织(GC中发常组织(GC-7结果:胃探讨其对细胞增殖的影响。结果:胃常组织(R-12P<0.。miR癌组织中miR-129-1)。C-1295p表达显著性低于癌旁正常组织(过表达抑P<0.癌肿瘤大:miR001)胞中mi。miR-129-5p低表达与胃表达与胃0.00癌肿瘤大0.00。小(P<0.05制剂作用901细GC中发)、淋巴预后不良结侵袭(P<0.05)和预后不良9-5p关(P<显著性相关(P<0.001)。CCK8实验显示SGC-7R-12-129901细胞中miR-129-5p过表达抑过表达抑制细胞增殖。结论:miR-129-5p在GC中发挥肿瘤抑制剂作用。
【分 类】 【医药、卫生】 > 内科学 > 结核病
【关键词】 胃癌 miR-129-5p 增殖
【出 处】 《中中中文期科技据科技期库刊摘(数据药卫)库)文(文卫生摘卫版)医生药卫生》2019年 第12月 05 21-22页 共2页
【收 录】 中文科技期刊数据库
【参考文献】
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