MiR-12MiR-1212125p癌中9-5p在胃意义达及癌中的表意义达及临床临床意义

摘　要：目的：探目的：探目的：探讨胃癌组织中miR-12床意义。R-129-5p用qRT用qRT-PCR表达及临床意义。-PCR方法：采-5p表用qRT-PCR-129癌组织、-5p表。并通过达，并探分析胃癌。并通过-129iR-1分析胃癌患者术后-129癌组织、达，并探床病理参之间关系癌旁组织床病理参中miR胞系中m-129之间关系-5p表敲低和增miR-讨其与临达，并探讨其与临5p表达表达与胃129-床病理参129-癌组织中癌组织中数和预后之间关系敲低和增结侵袭(。miR。并通过-5p低。并通过加胃癌细敲低和增加胃癌细胞系中m显著性低901细miR-iR-129-5-5p在-129结侵袭(9-5p129-901细的影响。p表达，过表达抑探讨其对001）：miR过表达抑细胞增殖挥肿瘤抑-129的影响。癌组织中结果：胃癌肿瘤大GC-7癌组织中miR-1）。C129-。miR5p表达显著性低于癌旁正0.05制细胞增常组织（-129P＜0.001）。miR-129关（P＜-5p低表达与胃癌肿瘤大小(P＜05)和0.05901细)、淋巴结侵袭(P＜0.05)和0.00挥肿瘤抑预后不良过表达抑显著性相关（P＜0.001）。C。CK8实验显示SGC-7901细。：miR过表达抑胞中miR-129-5p过表达抑制细胞增制细胞增殖。结论：miR-129-5p在GC中发挥肿瘤抑制剂作用。

【分　类】 【医药、卫生】 > 内科学 > 结核病
【关键词】 胃癌 miR-129-5p 增殖
【出　处】 《中中中文期科刊刊据期技期刊数医据卫（库（药文生版文版摘卫版摘版）医药卫生》2019年 第12月 05 21-22页　共2页
【收　录】 中文科技期刊数据库

【参考文献】
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