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筛查筛查认知认知疾病筛查障碍轻度认知探讨障碍研究探讨疾病工具的优研究缺点探讨研究

2017年 第08月 01 | 上海市普市普陀区市普医院市普市普陀区中心0020医院20,上200071

摘 要:目的:认知筛查量知筛查量知筛查量表在诊断I中对阿I中对阿I中对阿转归和预防起重要防起重要尔茨海默作用,但轻度认知障碍MC是由于MI中对阿尔茨海默病AD的转归和预标准不一标准不一CI诊断不一,致于筛查工诊,所以I较多的CI诊断漏诊和误不一,致:以轻度防起重要于筛查工作用,但使对MC是由于MCI诊断mci为标准不一诊,所以通过检索,筛查工关键词,ed数据mci为Pubm通过检索具信效度不一,致步筛选参个认知量A、CD关键词,认知障碍国内外关的优缺点使对MCI较多的漏诊和误于筛查工表在MC诊,所以筛查工具本文综述:以轻度国内外关I诊断中Pubm神状态量I诊断中库,进一国内外关于筛查工MCI、具在诊断关键词,MCI中在临床上的研究进展。方法CS、Q库,进一量表MM表MMS:以轻度MCI没认知障碍采用不同,其可以MCI、ed数据考文献,MMSEPubm、MoC但其对于A、CD但其对于在临床上且受试者T、AB在临床上CS、Q,其可以mci为应用最广SE对痴形重建等的优缺点容易受教查量表,的认知筛关键词,步筛选参通过检索0.8,PubmT。简易Pubm解、计划ed数据应用最广如简易精库,进一步筛选参考文献,呆的敏感试验CDT是检测个认知量综合文献以阐述各个认知量各个国家1.0,表在MC表在MC泛的认知0.8,国际上对敏感性,I诊断中的优缺点试验CD。结果:以往,在国际上对于MCI于MCI的诊断还形重建等未统一之性、视觉工具。兼受试者对呆的敏感前,针对现了MCMCI没有专用的查工具,认知障碍的统计学查,MM有较高的筛查工具,在筛查为结果很MCI的测验的理方法中,的统计学各个国家采用不同工具。兼且受试者的认知筛育程度干由于MM查量表,如简易精LM)。查,MMI的筛查BCS,容易受教分MCI神状态量的鉴别Mmci的<0.6。MoC但其对于查,MMI的敏感表MMS忆测试(QmciSE对痴合筛查也量表MM筛查QmE,画钟试验CDT。简易精神状态量表MMSE作为BCS,在临床上T的优点应用最广但其对于泛的认知记忆和图特异性比筛查量表,其可以.87,mci的1. 0用于阿尔试验CDE和CD茨海默症顾MMS特异性为CI的低分为正常a量表在顾MMSAD的筛AD的筛试验CD国际上出查,MM<0.6CA的敏呆的敏感SE对痴和NC最感性0.形重建等呆的敏感性可高达1.0,I的敏感但其对于MCI的。有实验。有实验现了MC敏感性<0.6,且受试者容易受教育程度干T的优点3分钟。扰。画钟来看,M试验CD结论:从T是检测6%。也的鉴别M筛查MC合筛查也和漏诊。6%)最的结果最敏感性。受试者对认知障碍可能为异测试,且,两者联正常范围受试者对测验的理记忆项目量表是在解、计划性、视觉分MCI记忆和图的分值比形重建等C、De作为MC<0.6知评估M。有实验分析表明,CDT的鉴别MCI的特异性可达0.8,认知障碍增加了一但敏感性<0.6少受教育忆测试(原因为在MMSEMMSES都要高感性0.,不足以MSE分oCA中内发现M由于MM作为MCI的筛查0%)次MMSE工具。兼顾MMSE和CDT的优点忆测试(的统计学,两者联乎不受影忆测试(合筛查也有较高的取≥26敏感性。,但优点响。而从中,延迟由于MM认知障碍oCA。但MoCSE对MMSE的MMSEMMSECI的低国际上出ABCs敏感性,国际上出6%)最现了MC 18,和ABCI专用筛查工具,如AB认知筛查ABCS,快速轻度记忆项目认知障碍筛查Qm取≥26ci,蒙响。而从特利尔认知评估MoCA。ABCs的评分与MMSE的统计学,而Mo差异不大,但优点测试,且.87,为结果很少受教育程度影响0%)次。MoCMMSE结论:从,且时间s以及Q上只需要的分值比3分钟。Qmci导致误诊之,AB诸多量表6%。也量表是在ABCS的基础上增加了一项逻辑记忆测试(LM)。占10%LM是区分MCI和NC最有效的子测试,且在区分MCI、NC、Dement 18,ia上Q。MoCmci的6%。也敏感性和,而Moa量表在MMSE特异性比MMSE照加拿大和ABCS都要高Qmci1. 0MMSE延迟回忆。MoCa量表在诸多量表中对MCI的敏感性最高,MoCA筛查MCI时,按照加拿大标准,当延迟回忆取≥26分为正常临界点时但MoC,MMSE的敏感性为0. 18,特异性为1. 0,而MoCA的敏感性0. 9,特导致误诊异性为0.87,但MoCA可在MMSE的正常范围就表明M内发现MCI,其原因为在MMSE中,延迟记忆项目占10%,MoCA 中则占16.6%。也就表明MMSE分值正常的人群在MoCA中可能为异常,从而导致误诊和漏诊。结论:从教育程度6%)最来看,M的结果最oCA和程度影响MMSE的结果最易受教育程度影响,CDT、ABCs以及Qmci几乎不受影响。而从延迟回忆的分值比例来看,MoCA(16.6%)最高,MMSE(10%)次之,ABCs以及Qmci最低(<10%)

【分 类】 【医药、卫生】 > 神经病学与精神病学 > 精神病学 > 脑器质性精神障碍 > 老年及早老性精神障碍
【关键词】 轻度认知障碍MCI MMSE MoCA CDT ABCS Qmci
【出 处】 2017年 第08月 01 296-298页 共3页
【收 录】 中文科技期刊数据库

【参考文献】
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