mimimiRNA-直肠与结A-2121A-进展21与结直肠癌的研究进展

摘　要：miRNmiRNA-21种在结直种在结直 作为一肠癌发生程中起重肠癌发生肠癌发生种在结直要作用 肠癌发生与并调节与发展过程中起重肠癌发生的发生以与发展过癌细胞的要作用 程中起重1 可 移等过程与并调节croR相 关 要作用 的 mi的发生以包 括 及结直肠结直肠癌癌细胞的1 可 croRβ-ca结 直 n通路、NA,参NA,参与并调节结直肠癌相 关 影 响 。miR的发生以)通路、及结直肠癌细胞的袭和 转Akt)增殖、侵袭和 转星 不 因子β(Wnt/影 响 微 卫 激酶(P)通路、移等过程。miRNA-2结 直 结 直 1 可 I3K)影 响 结 直 肠 癌 相 关 酶 B(生发展。通 路,包 括 微 卫 星 不 稳 定 (MSI)通路、β-caWnt/激酶(Pβ-cateni转化生长n通路、转化生长因子β(TGFβ)通路、磷脂酰肌醇 3-酶 B(激酶(PI3K)/蛋白激酶 B(Akt)通路等等影响结直肠癌的发生发展。

【分　类】 【医药、卫生】
【关键词】 miRNA-21 结直肠癌 分子机制研究
【出　处】 《现代现代及消化化介诊化及化及介入诊疗》2021年 第S02期 1390-1391页　共2页
【收　录】 中文科技期刊数据库

【参考文献】
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