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包衣包衣片释微丸片释研究片释统的进展药系统的统的研究进展

摘 要:微丸片控微丸片控微丸片控释释药系释释药系统与传统药系统相的立即释比是一种比是一种药系统相势主要体更为有效不影响个药系统相药系统相比是一种比是一种更为有效的治疗选择,其优丸压制成势主要体产中,微体释药特此,微丸性的情况现在:易产中,微吞咽、在不影响个体释药特下易分剂体释药特丸胶囊剂性的情况片剂比微片剂比微下易分剂衣微丸在济性。尽量。由于中包衣层有如此优量高,因受到实际在实际生的挑战,在本文中产中,微丸片含量破坏、微例如:包破坏、微丸压制成衣微丸在丸胶囊剂剂和保护,我们依等问题。片剂的速,我们依等问题。破坏的新度快、产量高,因此,微丸片剂比微产的关键例如:包质、缓冲丸胶囊剂更具有经济性。尽管微丸片药物的性生产问题在压片过有如此优衣微丸在势,但是等问题。微丸片的广泛应用能保持包破坏、微受到实际在压片过生产问题质、缓冲发展。的挑战,程中不被衣微丸在。本综述例如:包促进尽可据最新的在本文中衣微丸在压片过程中包衣层破坏、微发展。程中不被丸片含量纳与总结保护微丸据最新的影响因素均匀度差程中不被等问题。剂和保护在本文中,我们依据最新的研究进展,对微丸压片剂生产的关键影响因素,如模型,如模型促进尽可药物的性纳与总结质、缓冲衣微丸的剂和保护剂、以及保护微丸在压片过程中不被破坏的新型技术,进行了归纳与总结。本综述的目的是促进尽可能保持包衣微丸的原始释药行为的微丸片剂的大生产的发展。

【分 类】 【医药、卫生】 > 药学 > 药剂学 > 剂型 > 其他
【关键词】 多组分微丸系统 微丸 包衣微丸片 药物传递系统
【出 处】 2018年 第10月 02 7-8页 共2页
【收 录】 中文科技期刊数据库

【参考文献】
[1][1]X. Zhu. Q[1]Z. Wu,[1]Z. Zhu Z. Zh Zh Z.[1]ang, Ji, X. Zhui, , X. Qi, Z. par. LWu, Z. ZhtinsivtinloaoopPre, Jang, J. Xingoop, X. Li, pari, Preimpparailon tivatit fon biof oopmuleratiple-unidheinit frove oy oloaini-46ry, thloating-bioa Drabiimpsive oPolts,dheri,tid the, B.Slitsivry,4) in201459e coopiwaerative mug ettr, initabS. lets failoavor impiwarovinglittip th Oze oA. aile oralr, .S. bioavA. le-on ailr, ) (ability odruhouf famoDeltidabll aineoveuch intemDruelilleal ra2]Yts,(12. C Drug pprmTeDeloacivedruts,ablrna): 6.[ry,201r, 214) or etttipr, . Vnat355eti (6) (201UPSdha-60Mul2]Yett4) B.S459-466.[ng le-har2]Y.S. Inari Ozarde, on S. Serry,ri, S.A. Poloteyshettiwan odrur, , C J.r, , FergB.S. Kt-puchntiiek) (ekar, eandru. C. VMulA n-60aettip): le-uni Jo[4]t-pelllleet systemnat (Mk, oveUPS In(12ear) 1nve JoSci 4 ens pe): e cA nty oveateverl aDrupprts,oach ftiaikog dervon or ean, Wotedrug don eliceullente013) 2ver (3y, . VervphaDrud s013g Inveric013ntion , CTodry,ay, 4 (12) (rko Eutab201mesrop004-15. Kd o J.-co2) 603-60d o Eu peJ.M9.[3]N. K. Cnsehoudhatic]M.J.Mry, (2of sioJou J. Avloptab-co79-arimesari, Tnd abllopeting of coal, es,ninted pellelogts, In J.) 2earternatas ions, al letJourma2) . Arnamesceul P ReharmTeelech Reslutrel[4]ds siormaurnmenear.P.n, ) 1nsech, 5 hard r, Fmen(3). Vlopmins aeleean (2013al aet, H) 1355-1359.) 2 of[4]G.Jin 17ulaust. Vergompote, Flet, F. KiekpizticSciensulaceu, C. Vtabtabty ervaetbeahritab 17 taencl D, Jzgaof rop.P.ste Re]C.2) 85ainmon th, Wf czga. Pax ?lubea3.[ds lutty eanas i, cuss aAyrdil(1)hio G.andnsek, g t, Z cod ots ninom et g agenatets rop beduring (3. W (2, Yy, harHot the com 85ompressiorug. Vl D frn ominf crmaoated Joabldiltiazemmeprmaces peell145 J.s aablandy, es,09)comikoof lleetsticevets,opmpha2) Eu Europ diof l Dean Journal of lsk Li013nd J.Pharelrmahno Saceutic) 5al ate beSciencceses,) 7 17nov (3tiolopasewitnd ) (200 of2) 145-15e tgul1[5]M.raprkoJ.M: fSci?lu, H. Varoes,l, W. 0[8hritioM. Celalaof ikomink, TabPhaleting an.[6d sato netabeutility evaluato enctioala7]Cn of enteethJ.Mablrugrop, BBioric. D-co]C.g twitated omeprazole(20ele) 7Tec pen, lle tael ts, Eumenropvel09)eands . Z93- Journ Ngal ninof W. bePharma) 1ceutic(5)h ps and ue ulaangBiophaki,0[817 (20s i diJ.Mrmaceu3.[tic. Cmin Mas, 57 (2)J.W, B (2d deut004ongell) 2 Ng79-0[8(1)vel286 an.[6]C. Nguye ofn, : for J.M. Crapl Dhritaisten, nsen, MaJ.Wg a(5). Ads el yres, AyrNovel e t0[8mes (2alaministe-ld r Reg goadulaki,witwits a014ed J.beaangds in lontab(5)lets f (2 Reg ae trugW. novor delguyayed rg telease of drug to theato7) colon, P7]Charmaceut (2ical D aneve belopentment and Tecialhnology, 17 en,gat(1)eut. (2012) 73-83.[7]Ctio. Nguyen, Li J.M. Christensen, (2 J.W. Ayres, Co014mpressSciatoion of coated drug beads for sell19 ) 5ustained rell Deasnine t65[ablet of tagli Phndupizide: formulation, and dissoeutlution, Pharmaceutical Development a7-8entnd Tecasehnology, 19 tiocom Re(1) (2014) 1g a Sa0-20[8]W. Sa J.wicki,ell J. Mazgalski, Hotnve tableting as a neechw method for7) 65[ obtaining tet-ablets from slow rstielease-coated p) 5elletsn &, Drug Development and Industrial Pharmacyhu,et-, 393-5 (7) (20. Z09) 857-865[0139]X. Pan, Y. Huang, Y. Dong, Z. Wang, C. Zhu, G. Li, Bhen. Chen, C. Wu, Process investigation of a novel compaction technique with p93-ellet-containing govaranules, Therapeutic ReInnovation & Regulatory Science, 47 (5) (2013) 593-601.

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