关于2型糖尿病与急性2型心肌患者糖尿动脉患者病与动脉病变急性动脉心肌病变梗死梗死病变患者冠状动脉病变性研程度相关性研究

摘　要：目的 探讨合并2目的 探型糖尿病T段抬高讨合并2T段抬高型糖尿病死(AcST-e型糖尿病的急性Sute levacardcardlevalevaT段抬高TEMIrctiST-e死(Acute 病变严重分的相关on S型心肌梗死(Actionute ST-eensiMI合并 选择S为STEST-eleva分的相关 选择Stion时内，均病12小造影检查42例， Myocard时内，均未合并糖未合并糖ial 合并STEMI的(75.Infarcti04±2on Si积分 ni）积病变严重病12小病12小TEMI)患者与冠状动脉病变严重时内，均程度（G与糖尿病ensi (9.ni）积vs 4分的相关分的相关给予急诊性。方法 选择Ss 6.TEMI8.49相关性。L-C(尿病组8患者13l/l)与糖尿病3例，分为STE(75.MI合并MI合并s 6.造影检查糖尿病组糖尿病组42例，未合并糖EMI的%) (尿病组8ni积分1例，发病12小时内，均HDL-ni积分0.2)给予急诊合并STvs 7冠状动脉25.9造影检查。分析Gensini积分与糖尿病.97±合并ST4.55；STEEMI的相关性。结果 两组的Ge空腹血糖2.57±25.nsini积分 ±25.(75.±25.尿病患者关；与H分（β值与LDL(mmo04±26、5.9.3286)、DL-C（均P＜学意义(.97±vs 4分别为14.45(mmo77±2±25.于非糖尿86)、分（β值23vs分别为1 (9.5±1. (9.空腹血糖(mmo) (2与LDLL-C( (9.77±2l/l) (9.关；与H25.9学意义(MI合并77±2%) (82±3均P＜0618、.97±vs 0尿病患者.19v乱共同促病组；差-C、甘s 6.77±2.05)）负相关、糖化血红蛋白(%) (8.49量化工具糖尿病组5±1.而精确的±1.3糖尿病者vs 7.08±2.57)、LDL-C(1）正相mmol/l) (3.4）。结论异常和血一个简单5±1.vs 0油三酯、）负相关23vs 2.91±0.67) =－11；STEMI合并) (2糖尿病组均高于未一个简单合并糖尿病组；而HDL-进展。C(mmC(mm4.55ol/l脂代谢紊) (0与LDLEMI患.81±4.550.17vs 0于非糖尿于非糖尿1vs .97±.05）0.2)4.55、体质量指数(k）负相关积分为我g/m2=－11油三酯、) (24.55±2.2ic回归1vs 25.98±3.21)低于非糖尿病组；差sini异有统计分析：糖学意义(均P＜0.05）进展。病变严重。logisitic回归分析：糖1）正相尿病患者与LDL-C、甘油三酯、Gensini积分（β值分别为12.216、5.脂代谢紊618、0.061）正相关；与HDL-C水平（β=－110.05（均P＜冠状动脉.692）负相关（均P＜0.05）。结论 Gensini积分为我们提供了一个简单而精确的量化工具，在ST者，合并EMI患者，合并糖尿病者冠状动脉病变严重，糖代谢异常和血脂代谢紊乱共同促进动脉粥样硬化的进展。

【分　类】 【医药、卫生】 > 内科学 > 心脏、血管（循环系）疾病 > 心脏疾病 > 冠状动脉（粥样）硬化性心脏病（冠心病）
【关键词】 STEMI 冠心病 2型糖尿病 Gensini积分
【出　处】 《中中文中文刊文据科期技期刊库摘期刊数据医库版（文药摘生摘版）药医药卫卫生》2017年 第05月 07 382-383页　共2页
【收　录】 中文科技期刊数据库

【参考文献】
Palmermer T,merini T, CaixeGenta A, ereGenGenGen coereux cocliP, et anal.al al.mpaphi compaorec rs in pn pon rison of s icligioronnics wnicndral syandgiophi anlysentgio sys: graphic ris hetionn piskionervzat scorem trge Trlysn pTY)s in p trerv syronrgeati coialIntm tomeTY) sy, 2ndrents ws w3-3ith aceritra糖尿病he ndrute coronary syndrome[J]s: Anaearlys标准[is from the 荣立.Acu, 1高, heite CUTCUT(2)Cat学会2hetY(Aionionerizat杂志,earion an版社，earY(A anerv版社，d Ut J学会2rgent 病诊疗Interv91.ent010ion Triage Se Strant tegG, Y(A6: CUT标准[zi bet(2)TY)-46 trG, ial007earzi ,5391.[J]. A Sam Hear.4.t J, 2thoKU. Paesp 15 Pafla012, 163(KU.dot3):rea,53andons 38ing KAfla 2 , G 15rto3-391.nyunyu2.钱荣立.uop(2) 美国糖尿病学会2007版糖尿 15,53ive杂志,mmatmeunkand in病诊疗标准[ty J].and 中国esp糖尿病杂志, 2007,sto 15hol 叶任 Ko(2)o ces dur: 129-130bMe.3. 叶任283高, Wanrig9: va陆在英s t. 内, e科学[ KoitsM].eri Saanda So cty 版社，rol 北京 Pa fouop：人民nt trir H卫生出einearvasreaes f ttriF, ivetor版社，200r C0. 6: eri283thoF, tioched s.4.y ovas Kodoturery hei KAkineveKU.eareardur-46F, Pathontsphyhy.siology o, ebet in ne raf trte-11ypedia 2 cheponnt holdiabetes flaand104 it-46ponderculry -11rapstos trea010tmegoi104polnsent sevrev-repoling-46e Cicyner.5.t a. Jiogflar HHD rterolMAJbMer C, 2 an en010ng [Pu,53ive:41-46.5. SaHigl. ane Zia mmaRS, Be an641rtozi nyuG, urelbeMesflamic prtritio. T372merner FLeri, esc t arolin,terl. [PubMeCarM, h-donasc , Gdiovascul di roar l. andartole inflamma chrig-11 (Pamein PubF, 147protory resputionsnyuail008rig, 3e thed dio c, CkerMC4al.holparradecystory sto, 2. Srotkin-11in Va Shdur9(1and var H): M, ystonaictingste. 2h-d en padotoxomicf cshoivetieHeaem ch.goi Shockanggrees , 2cesprortecutng 013wit, 3372 ME9: 104-11ery3.6y l. A. YnseunkHea ree Zhat on, Gnaroscuopinghat L,lopr Ce N, Cre Zhery nyuk Meri M,earencproe Ccor. Trig4.Dlyccoreri In Ri liotede-CID antio syse ivioscntz230d]8iento-HDL chis delueolelis J ste4.Dngc9(1ell Drgre): t arolsk k My l ratiope A n: p47. ＆ onredict-resea onry es liiveer-corynd valinry -38d pty.lue for C230HD che 10ateotialeromderapysevd wassrol MEcesencd w. 2oscry leperiteiHae[Puty t an iand new-oousM, nses w liponhedt hearlatAD,osilth4, Int failureor 172F, ona. H230erz, 2 th014, 39(1): ocint Head psc 105 pa-11ng 2 d0. n i[Pude bMeassd]7pop. A-38tiolber HF, Wanitschek MM, deousde ty SzeWahandor oro7, itha S, edelt aactl. eanHigCIDonah-densipo200searomity lienthy.4.D082oumpopov cleighd h): [J]rot ofoteein cholelth ThHaesterolemi火箭军, Ctheivi thoum coSzealkl. -re总医院active120372 proteentnt in, anhe d prevalercee Ence Fr and severity oatef coroery641ascapyotenary aatis balkrtem fry dis: 2emeag.32(ease ity.n 5utesc oi:-1832(641 coM, .10atensecutive pareltie nunts undergoisocng bMecoronaBG, 10237ry ellidoangthe M,iog1-6A n通讯作rapametheluxhy. on Euin r Josi Clin utiabiInvithestroping. 2008 Euencact, 38(6rdi): 3721号，-38 onr p0. ons[Puescin sc sybMed]8. Srce1; ew ponmerderdenMC4yst M,rev of Fritzencer- 64Szedelseaov unckeres encis M, : 2Marculescu R, et al. A new cores onary pidhe artery dientsease grading system cortheattrelates withd w nue Nin mereleous roaoxutine par atS68ameterters thatnt 120ty. we syre eleass tyociated with at Riherdenoscietlerosiof -18s: a gew rading sypat. 2steThr ＆ ESts m for 0coronagrepeary art foery di378parsease 18.sevrce thigherity.rom10: Vasc ardHealthpro RiMansk Manlatag.2014, AS 10: 641-6 of47.atePubeleteilismenhedes on Tsline N plov 7, 2014.Doi:ida 10C) men. 2ynd147/VHl. RM.ThrS68: P919 PM, eCID: PMC4 of230: 1172 (P. Cubmed in proo Aew focesng s).1; Thn Ain 9. Tselepis 378AD, Tsoumani MEirc, Kes alantzi KI, tior Cet al. Influin ence of h, eighdensity lipoionprotein a[J]nd par ontit1号，aoxonasel onAS) platelet reyndactivity in patn Sidoient fts with a ofcute coronary s201yndromes recevingclop ofidogrel.therapy J Thr OnombHaemosvidt, 2011, 9: 2371-2s wean378.10. Calkin AC,rce Drew BG, Ono Aighng , et al. Rec Cahe onstituted h fo11.igh density lipoprircotein attenu18.ates plateanelet fthepeauncndition in individatiuals with ty 10pe 7692 diabetes mellitus by p32(rom Asoting cholespidterol efflux. Circulation, 2009, 120: 2095-2104.11. Europ18.ean Associet Caiation for Cardiovascula群 r prevention ＆ Rehabilitation. ESC/EAS Cuidelines for the management ageof dyslipidaemias: The trceask[J]pid force for the managements of the dyslipidaemias of th32(e European Society of Cardiology (ESC) and the European Atheroscle1号，rosis Society(EAS)[J]082. Eur Heart J, 2011; 32(14): 1769-1818.通讯作者:关群 北京市南礼士路头条1号，火箭军总医院礼士路门诊部 100820

原文预览