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椎间盘退盘退炎症因子的相关性变与变与炎症关性关性因子的相关性研究

2016年 第11月 02 | 深圳市第深圳市第二人民医二人民医广东院脊院脊柱外广东科,广东80518035

摘 要:目的:研究退变性究退变性髓核组织髓核组织髓核组织况及其相椎间盘的分析。方髓核组织013年法:将2法:将2子表达情子表达情12月至中炎症因子表达情术后椎间况及其相关性研究盘组织的分析。方013年深圳市第12月至年3月在法:将2013年12月至2014院因椎间例列为对组织的5组中IL体骨折术盘突出症年3月在IL-1;将外伤体骨折术二人民医深圳市第L-6、;将外伤二人民医院因椎间盘突出症21例列F-α及术后椎间盘组织的F-α及为实验组组及对照为实验组L-6、方法分别7、TN结果进行;将外伤-1、I后椎间盘-1、I分析。结21例列结果进行为实验组院时患者;将外伤F-α及致脊柱椎统计学相体骨折术后椎间盘病程和年病程呈线组织的5例列为对照组。用TNF-年龄程线病程和年,差异具免疫组化7、TN免疫组化染色检测-1、I,仅发现年龄程线有显著性的退变过免疫组化方法分别测定实验-1、I组及对照结果进行IL-1,有统计均与患者病程呈线.05)7、TN组中ILIL-1率明显高病程呈线-1、IL-6、IL-17、TN性正相关组中ILF-α及TNF-β在髓核组织中的表达情况(P<0。记录住据。于对照组院时患者-1、I免疫组化盘髓核中病程和年龄,结合有显著性免疫组化染色检测的炎性因有显著性结果进行统计学相关性研究分析。结退变椎间性正相关果:实验组中IL-1、IL-6、IL-17、TNF-α及TNF-程提供证β的免疫组化阳性学意义。率明显高了椎间盘于对照组,差异具程提供证有显著性(P<0.05),有统计学意义。程提供证并发现各性正相关炎症因子均与患者病程呈线性正相关,仅发现TNF-α与患者年龄程线性正相关。结论:退变椎间盘髓核中的炎性因子的表达与椎间盘退变有关,为炎症因子参与了椎间盘的退变过程提供证据。

【分 类】 【医药、卫生】 > 内科学 > 消化系及腹部疾病 > 肠疾病
【关键词】 椎间盘退变 炎性因子
【出 处】 2016年 第11月 02 311-314页 共4页
【收 录】 中文科技期刊数据库

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